M. R. Torres1, H. Aziz1, V. Nfonsam1 1University Of Arizona,Tucson, AZ, USA
Introduction:
Colorectal cancer (CRC) is the third most occurring diagnosed cancer and the third leading cause of cancer related deaths. Despite the efforts to improve preventive methods and treatments, disparities still remain in CRC incidence among different races, particularly focusing on stage at presentation and anatomic location of the cancer. This study assesses the disparity in incidence of CRC among different races in the state of Arizona.
Methods:
A retrospective analysis of CRC data from the Arizona Cancer Registry (1995-2010) was performed. Races identified from the database were: White, African American, Hispanic, Native Americans, Asian, and Pacific Islander (PI). Early stage colon cancer was defined as stage I and II, while advance stage was defined as III and IV. Using logistic regression modeling, differences in tumor characteristics were assessed among different races in Arizona.
Results:
There were 39,623 reported incident cases of colorectal cancer during the study period. There was a significant decrease in overall incidence of CRC among different races. The Hispanic population presents an increase in incidence of early stage Colon Cancer (3.8/100,000 to 4.7/100,000) and a decrease in the advance stage Colon cancer (10.6/100.000 to 5.6/100,000). The African American population has an increase in the early stage (10.3/100,000 to 11.1/100,000) and a decrease in the advance stage (17.4/100,000 to 15.4/100,000). The Native American population shows an increase in the early stage (4.6/100,000 to 8.7/100,000) and an increase in the advance stage colon cancer (10/100,000 to 10.4/100,000). Asian/Pacific Islanders have an increase in the early stage incidence (2.8/100,000 to 6.3/100,000) and a decline in the advance stage Colon Cancer (10/100,000 to 9.5/100,000).
Conclusions:
Overall CRC incidence is trending down for Whites, Hispanics, African Americans, and Asian/PIs, except for the Native American group.