68.05 Comparison of Outcomes in Colorectal Resections Based on Surgical Technique.

S. Groene1, C. Chandrasekera1, T. Prasad1, A. Lincourt1, B. T. Heniford1, V. Augenstein1 1Carolinas Medical Center,Division Of Gastrointestinal And Minimally Invasive Surgery,Charlotte, NC, USA

Introduction: Laparoscopy has become a common technique for many colorectal resections. Robotic-assisted colorectal surgery is also gaining traction. The aim of this study was to compare outcomes following colorectal resections based on surgical technique.

Methods: Review of the Carolinas Medical Center (CMC) NSQIP data for colorectal resections performed from 2013 to 2015 was conducted. Data were classified as open (O), laparoscopic (L) and robot-assisted (R) cases based on CPT codes and chart review. Demographics, pre-operative co-morbidities, minor and major complications were evaluated using standard statistical methods.

Results: There were 616 patients: 371 in L, 212 in O and 33 in R groups. There were no differences in age, BMI, race or gender. The groups differed in rates of pre-op sepsis (20.8% vs 0.8% vs 0% for O, L and R, respectively; p<0.001), contaminated wounds (53.3% vs 11.9% vs 3%; p<0.001), ASA class 4-5 (29.7% vs 8.7% vs 0%; p<0.001), emergent cases (31.1% vs 1.9% vs 0%; p<0.001), smokers (25.9 vs 15.6 vs 15.2; p=0.001), pre-op ventilator use (11.3% vs 0% vs 0%; p<0.001), and pre-op transfusions (12.7% vs 3.2% vs 0%; p<0.001). Also, there was a significant difference among the groups in post-op transfusions (34% vs 10.2% vs 3%; p<0.001), superficial SSI (9% vs 4.9% vs 0%; p=0.05), post-op patients on ventilators at 48 hours (18.4% vs 1.1% vs 3%; p<0.001) acute renal failure (1.9% vs 0% vs 3%; p=0.001), UTI (9% vs 4% vs 0%; p=0.02), DVTs (3.8% vs 0.8% vs 0; p=0.04), 30 day mortality (10.4% vs 0.5% vs 0%; p<0.001), post-op sepsis (17% vs 4% vs 6.1%; p<0.001) and LOS (13.2±10.1 vs 7.4±7.3 vs 8.7±8.6d; p<0.001). After controlling for wound and ASA class and pre-op sepsis, multivariate analysis indicated that O cases had significantly higher rates of superficial SSI [OR 0.5 (95% CI 0.2,0.9)], organ space infection [OR 0.2 (95%CI 0.07,0.5)], post-op transfusions [OR 0.5(95%CI 0.3,0.8)] post-op ventilator use [OR0.3 (95%CI 0.7,0.8)], sepsis [OR0.4 (95%CI 0.2,0.8)] and LOS (p<0.001) compared to L cases. There was not a significant difference in anastomotic leaks among the groups.

Conclusion: Patients who undergo open colorectal resections are sicker and have more post-operative complications, even when controlling for ASA, wound classification and pre-op sepsis. Laparoscopic and robotic colorectal resections have similar outcomes.