10.14 Factors Associated With Failure-to-rescue in Patients Undergoing Trauma Laparotomy

B. Zangbar1, B. Joseph1, V. Pandit1, N. Kulvatunyou1, T. O’keeffe1, M. Khalil1, A. Tang1, G. Vercruysse1, R. Latifi1, R. S. Friese1, P. Rhee1  1University Of Arizona,Trauma/Surgery/Medicine,Tucson, AZ, USA

Introduction:  Quality improvement initiatives have primarily focused on preventing in-hospital complications. Patients developing complications are at a higher risk of mortality however; factors associated with failure-to-rescue (death after major complication) in trauma patients remain undefined. The aim of this study was to identify risk factors associated with failure-to-rescue in patients undergoing trauma laparotomy.

Methods:  An 8-year retrospective analysis of patients undergoing trauma laparotomy was performed. Patients who developed major in-hospital complications were included. Major complications were defined as respiratory, infectious, cardiac, renal, or development of compartment syndrome. Regression analysis was performed to identify independent factors associated with failure-to-rescue after adjusting for demographics, mechanism of injury, abbreviated injury scales (AIS), initial vital signs, performance of damage control laparotomy, and volume of crystalloids and blood products administered.

Results: A total of 1,029 patients were reviewed of which; 21% (n=217) patients who developed major complications were included. The mean age was 39 ± 18 years, 82% were male, 61% had blunt trauma, and median a-AIS was 25 [16-34]. Respiratory complications (35.4%, n=77) followed by infectious complications (45.1%, n=98) were the most common major complications. The mortality rate was 15.7% (n=34).  Blunt trauma, severe head injury, uninsured status, and blood products administered on the second day were independent predictors for failure-to-rescue. The overall failure-to-rescue rate was 3.3%.

Conclusion: The overall failure-to-rescue rate was low (3.3%) in patients undergoing trauma laparotomy. However, when major complications develop, uninsured status, severity and mechanism of injury, and blood product requirement are independently associated with failure-to-rescue.